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Eboka Talk / Iboga for food addiction on the horizon?
« on: October 18, 2013, 01:46:55 PM »
Is 'Food Addiction' Real?

Deborah Brauser
October 16, 2013

BARCELONA, Spain ? Binge eating disorder (BED) is part of the recently published fifth edition of the Diagnostic and Statistical Manual of Mental Disorders (DSM-5), marking its first appearance in any DSM. But what about binge eating obesity ? is it a type of food addiction? Should it be added to the next version of the DSM? Or is food addiction itself even a real disorder?

These are just some of the questions that were brought up during a presentation here at the 26th European College of Neuropsychopharmacology (ECNP) Congress.

Suzanne L. Dickson, PhD, told meeting attendees that because obesity has reached global epidemic proportions, there is an urgent need for understanding the mechanisms for uncontrolled food intake.

She noted that recent data have suggested that brain reward pathways that are involved in alcohol and drug addiction are also essential elements of the ghrelin responsive circuit. And ghrelin has been shown to both signal hunger and increase food intake.

"Based on these and other recent findings, could obesity be a food addiction? A subgroup of obese patients indeed show 'addictivelike' properties with regard to overeating…but this does not automatically mean they are addicted," said Dr. Dickson, who is a neuroscientist at the Sahlgrenska Academy at the University of Gothenburg, Sweden.

After the presentation, she told Medscape Medical News that more evidence is needed.

"Food consumption, unlike alcohol, cocaine, or gambling or Internet gaming behaviors, is necessary for survival. But we don't completely understand why certain vulnerable individuals become addicted, transferring something rewarding to becoming addicted to it. For drugs, it's much easier to separate what's going on," said Dr. Dickson.

"For now, we need to ask: in our modern environment where food is so plentiful, has food no longer become our friend when it is something we can become addicted to?"

More Research Needed

Dr. Dickson noted that past research has shown that 10% to 20% of obese individuals have BED, but the disorder also often occurs in people of normal weight.

The term "food addiction" was created by the media and some sufferers to better explain certain behaviors, and more research is needed to support adding the term as a formal diagnostic category, she added.
Dr. Suzanne Dickson

"The evidence itself is insufficient to support the idea that food addiction is a mental disorder. We do not have a clinical syndrome of food addiction so far, and it is very important to establish the validity of a condition before putting it forward for inclusion in the DSM."

Still, she pointed out that recognizing certain behaviors (such as gambling) as addiction is "a major step forward" and should help decrease stigma for these people.

Dr. Dickson is currently the coordinator for her university's integrated Neurobiology of Food Intake, Addiction, and Stress (NeuroFAST) project. One of the areas that NeuroFAST has looked into is the impact of palatable foods, such as chocolate, on brain centers involved in reward and addiction. They have compared overeating with drug addiction to try to answer whether obesity could result from a food addiction that resembles an addiction to drugs and/or alcohol.

"We had to ask if the evidence supports food addiction for more than a small proportion of the population," added Dr. Dickson.

"But I have to say that in man, there is no solid evidence that any food, ingredient, combination of ingredients, or additive (with the exception of caffeine) causes us to become addicted to it. That is different from drugs, which we know engage the brain and cause us to become addicted to them," she explained.

"Still, if we move away from food and concentrate on the individual, we can see that certain obese individuals express addictionlike behaviors."

Dr. Dickson went on to mention that a study published inthe Archives of General Psychiatry in 2011 discussed the Yale Food Addiction Scale, with validation from functional magnetic resonance imaging (fMRI).

"Looking at the brain response to anticipating or receiving a chocolate milk shake, they found some evidence that those patients who had a high food addiction scale rating had different responses to the drink than did those who had a low rating. But where are the cutoffs if we are going to use fMRI to help us?" she asked.

"I think increased research into BED and food addiction is needed, and it will facilitate new diagnosis and therapeutic advances for obesity prevention and treatment," she concluded.

"Stop Speculating and Overdiagnosing"

"I think from the perspective of DSM and diagnosis and classification, the main message for clinicians is to stop speculating and overdiagnosing things like food addiction or food disorders," session moderator Hans-Ulrich Wittchen, PhD, from the Institute of Clinical Psychology and Psychotherapy at the Technical University of Dresden, Germany, told Medscape Medical News.
Dr. Hans-Ulrich Wittchen

"It's too early. It's premature. It should be limited to what we know. And that is: binge eating is a stable behavior, and there should be intervention. Whether this is a behavioral eating disorder or part of a food addiction syndrome that we might diagnose in 10 to 15 years from now, we don't know," he added.

Dr. Wittchen, who was not involved with Dr. Dickson's presentation or research, was involved with the development of DSM-5.

"Eating disorders are considered more behavioral syndromes. The question is: does the fact that many of the eating disorders show many of the same compulsive and addictivelike behaviors justify putting them into the substance group in the manual?"

He noted that it is more important to find out what is going on with a particular patient instead of "getting caught up in semantics."

"It's difficult to say whether any of these food components have created some disturbance that would justify calling it addiction. Is this a brain disease by definition? I don't think so. That goes too far," he said.

"I think we should just understand what we can do to improve suffering in all of our patients."

In a press release, Hisham Ziauddeen, PhD, from the Wellcome Trust–Medical Research Council Institute of Metabolic Science at Addenbrooke's Hospital at the University of Cambridge in the United Kingdom, agreed with Dr. Wittchen overall. He noted that although the idea of food addiction is appealing, there is little evidence so far showing that it exists in humans.

"It is a very important idea to explore, but it is essential that we have sufficient research to conclusively support it before we hurry to recognize it as a genuine condition and start thinking of ways to tackle and treat it," he said.

Health Policy Implications
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Clinical summary compares both oral and biologic options.
Get the summary from the Agency for Healthcare Research and Quality

Still, Ashley Gearhardt, PhD, assistant professor of clinical psychology at the University of Michigan in Ann Arbor, noted in the same release that giving food addiction a formal diagnosis could someday lead to important implications for healthcare policy.

Dr. Gearhardit was lead author of the Yale Food Addiction Scale study mentioned earlier by Dr. Dickson and spoke at a later symposium at the conference about food addiction and BED.

"The idea that certain foods might be able to trigger an addictive process in vulnerable individuals is a hotly debated topic. If food addiction exists, it may alter the way we think about the role of the brain in obesity, which might open up development of novel pharmaceutical treatments," she said.

"Policy successes and failures from the addiction field might also guide approaches to this worldwide public health crisis."

26th European College of Neuropsychopharmacology (ENCP) Congress. Press briefing given October 7, 2013.

Eboka Talk / Anyone know anything about Costa Rica clinics?
« on: September 23, 2013, 11:58:23 AM »
I know Costa Rica is the place I need to go visit, and I hope that when I go, I can hook up with a kick ass clinic/ retreat where  I wonder where that conversation might go, but I wish I could get it started in the best direction.  I just want to get deeper into this thing because I understand its potential and even have a little know -how.  I think maybe I can help this movement push forward and my first instinct is to go there, so as not to reinvent the wheel, you know?  I wish I could hook up with someone down there, even just start a conversation about whats possible.  Just asking.  Thanks!   

Eboka Journals / Locked and loaded; Guidance please
« on: June 11, 2013, 11:14:35 AM »
Ok, game time.  Tonight I prepare.  ETA: tomorrow night.  Sitter is set.  Set is set.  Setting is set.  Nervous, but excited for another dance.  2nd time so I know a bit.  Will try to use what I know to go deeper.  I want to explore its depth and return anew.  The following week I will spend with family at the beach so I will get some good love and relaxin.  I hope it'll be a life changing experience.  Any advice would be greatly appreciated.

Eboka Talk / Naloxone/ buprenorphine vs Ibogaine
« on: May 16, 2013, 12:20:31 PM »
I wonder what your thoughts might be with regards to present day treatment missing the point that Iboga gets so well.

Buprenorphine, a schedule III partial mu receptor agonist, was approved by the US Food and Drug Administration (FDA) for the treatment of opioid dependence on October 8, 2002. Suboxone is the trade name for the preparation containing buprenorphine and naloxone in a 4:1 ratio, which was developed as a maintenance treatment of opioid dependence. First developed by Reckitt and Coleman (now Reckitt Benckiser Pharmaceuticals; Richmond, Va), buprenorphine hydrochloride was initially marketed as an opioid analgesic under the trade name Temgesic 0.2 mg sublingual tablets. It was also marketed as Buprenex in a 0.3 mg/mL injectable solution. In 2002, the Food and Drug Administration approved a high-dose formulation of buprenorphine as Suboxone in 2 mg and 8 mg doses (with 0.5 mg and 2 mg naloxone, respectively) and Subutex , a buprenorphine product with no active additives, also in 2 mg and 8 mg doses for sublingual administration.

The Drug Addiction Treatment Act of 2000 (DATA 2000) expanded the options available for the treatment of opioid dependence in the United States by allowing for private physicians to prescribe Schedule III, IV, and V drugs for the treatment of opioid dependence. Prior to this legislation, the only option was treatment through licensed methadone clinics.

The goal of DATA 2000 is to create opportunities for more comprehensive care of the opioid-dependent individual. Opening up private treatment options diminishes the stigma associated with opioid addiction, and opioid addiction treatment becomes mainstream. Finally, by opening up additional treatment options for opioid dependence, the demand for heroin and other illicit sources of opioids may be diminished with substantial impact on health care cost and other social outcomes. Currently, a maximum of 30 opioid-dependent patients can be treated per physician group, with the ability to increase that number to 100 after a trial period of 1 year.[1]

Buprenorphine is a partial agonist at the mu opioid receptor and an antagonist at the kappa receptor. It has very high affinity and low intrinsic activity at the mu receptor and will displace morphine, diacetylmorphine, methadone, or other opioid full agonists from the receptor. Its partial agonist effects imbue buprenorphine with several clinically desirable pharmacologic properties, including lower abuse potential; lower level of physical dependence (less severe withdrawal syndrome); a ceiling effect, with respect to clinical effects, at higher doses; and greater safety in overdose compared with opioid full agonists.

Naloxone has negligible bioavailability via the sublingual or oral routes and does not accumulate to clinically significant concentrations when administered in this manner. Naloxone was added to buprenorphine in an effort to deter intravenous abuse of this preparation.

Eboka Journals / I wish I would go again
« on: April 25, 2013, 01:49:57 PM »
I know I need to.  I know what I need to do.  I just dont quite do it.  I could use a little push, if anyone knows what I mean.  Good times, good times..

Eboka Talk / Psychedelic Retreat
« on: March 27, 2013, 12:44:08 PM »
I wonder a lot about getting involved with someone somewhere and do such a thing one day.  Somewhere safe and legal, and Im imagining a huge garden where people could eat fresh veggies out of, hot tubs and a sweat lodge, counseling, fire at night, tree houses, zip lines, & hiking trails.  With the general emphasis on connecting back to the natural world, breaking it down, simplifying the thoughts streaming through your consciousness, getting a grip, and rebuilding new bridges, making new better decisions for moving forward stronger than ever with the time one has left here in this realm.  Exercise, good nutrition, relaxing, and mind blowing breakthroughs, as needed, under expert supervision.  First though, I gotta philosophize about it a bunch.

27 million slaves, real slaves exist worldwide, many in guana, where Iboga comes from.  These people are forced to work and cannot escape their captors for fear of punishment and/or death.  The cost of their sustained freedom averages about 400 bucks per slave, but the real question is how can the world's most expensive military NOT be acting to extinguish this?? I woulda thought the first black prez ever might use his might for something so honorable...but its almost too poetic to expect, ever, sadly.  If you have a few minutes, this'll blow your mind...The fact that its so rampant in Guana I find interesting for our purposes and for what the root teaches us so far away.. I find it obscene that I never knew it still exists and even thrives.

Eboka Talk / so much research agrees & still it is the way it is
« on: February 28, 2013, 11:26:04 AM »
Ive been scouring through the research at pubmed.  This is where all the medical journals can be accessed by all to see.  When other medicines have proven their efficacy, they are pushed through the process by big pharm with big dollars.  With Iboga though, is it really the patenting problem that keeps it from becoming the legitimate for big pharm to make big profits from?  Ive heard that if it cannot be synthesized in the lab, then it isnt worth the money necessary to push it through. 

And maybe its better this way too, but Im left wondering why since the research has been done and its like even over done no more research is even necessary now.  It just leaves the elephant in the room about patenting and profits.  Maybe I answered my own question, and its better that we can control it ourselves, outside of big pharm's tentacles.  Ironic too, since addiction is the same thing as uncontrolled growth which is synonymous with the madness of the corporate charter; perhaps the greater issue all along. 

Our culture has inflicted upon itself a plague of not-enoughness, and yet just before we are irreversibly terminal, we realize a possible cure. Hmm, the irony is astounding!

Eboka Talk / Eric Taub in costa rica
« on: February 01, 2013, 12:14:09 PM »
I heard this guy is the man.  Anyone hear of him?  He's got a great reputation.  I wish I could work alongside his cota rica outfit one day.  Apparently he is mostly at his other clinic in Italy, but I just like the idea of living in costa rica better than Italy.  Anywho, just wondering if anyone's ever heard about this cat.  From what Ive read, hes made some waves in this field, akin to another great leader ahead of his time by the name of Lotsof, who recently passed, but once took Iboga to the masses.

Eboka Talk / how do you find a treatment center?
« on: December 14, 2012, 03:44:09 PM »
I want to find treatment centers..not to get myself treated, but rather to see if I can help them.  I love the idea of helping others in this way, the way that it has helped me.  I have found out that with the help of a beautiful plant, one can find cleanliness again.  It has shown me its possible to feel this way again, and I never expected that I could ever wash that shit outa me.  Now that i know I can, and how to do it, I want to spread the word...And without reinventing the wheel, I figure the best way to do it, is to contact some already operating treatment centers and see if they could use any help.  If anyone can help me get pointed in the right direction, I would greatly appreciate it!  Thanks again for everything this awesome sites represents!!  Cal, youre the best brother!  God bless ya!

Eboka Talk / source for chaliponga leaves?
« on: August 04, 2012, 12:45:25 PM »
Anyone know a source for chaliponga leaves?

Eboka Talk / RELAPSE!!!!!!!!!!!!!!!!!!
« on: April 11, 2012, 03:01:12 PM »
Its ok.  At least these are the times it becomes clear that addiction has assumed some sort of control over some part of me in the control tower.  But then, that gives it too much credit.  Many addicts relapse, but no one talks much about it.  Its ok, next time I will be better prepared, and with stronger will.  I will have to visit Iboga land again, get me some new flaps.  Gotta go again.  If at first you dont succeed...try, try again!  -Will report on my success once achieved.

Eboka Journals / HOLY SHIT FLOOOOOOOOOOOOOD!!!!!!!!!!!!!!!!!
« on: January 10, 2012, 11:09:35 AM »
OK, so now I know what a flood is.  HOLY SHIT!!!!!!!!!!  I heard them working on my mind and at one point, they were telling eachother I had some 'missing flaps, missing flaps,' they kept saying.  I had read about the visions of little workers cleaning up and fixing up your brain and it fit well.  Anyone have any idea what missing flaps means?  Anywho, they fixed em right up so I guess I got me some new flaps!  Woo hoo!  HCL was a hard ride all with tears streaming down the face, up all night, purging and shitting, but it was a landmark for me.  It was a great experience.  Thanks Cal, for all your help and everyone else around here thats been so genuinely helpful!  Youre good people!!  Spread the love!  & Get yer flaps fixed!

Eboka Talk / microdose success!
« on: November 22, 2011, 11:02:31 AM »
Screw the extracts!  I mean, I shouldnt say that since I have no idea about them, but from microdosing alone for 4 days nightly, I have no urge at all to partake.  My mind is clear and I havent felt this great in years!  This stuff is a fucking miracle!  Medical science can keep its head in the sand for all I care but they're really missing out on a powerful anti- addiction medicine!  I cant believe it! 

And in my research (mostly in this place), the extracts are all anyone talks about.  I think thats a shame.  I still havent experienced a flood however, so maybe when I do, I'll understand why.  I just wish it could be better displayed for beginners that if they cant take a week off work, that microdoses of bark daily (just 4 days is all it took me for the pull from within to cease!) is still a POWERFUL anti- addiction medicine, like no other.  Im glad I went this route because now when I do flood one day, I will remember the plant's essence; she will be familiar to me, like old friends. 

All hail Iboga!! 

Now, its time for a booster, and I think thats what this nagging headache means (~7 days later).  I am going to order some chaliponga leaves and make some Aya soon, as well, (as sorta another booster at about the 7 days mark). 

And I cant help thinking some psilicibin might go down nice right about now.  There appears to me to be again, some relationship, just judging from the feeling of the whole thing.  And Oh what a feeling!  It sure is a powerful medicine.  Thanks Cal!  -Freedom!

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